Chez CAPSULAE, nous sommes fiers de mettre la science et l’innovation au service de grandes causes internationales, telle que la lutte contre le paludisme.

Après une première collaboration fructueuse avec la société Faso Soap (désormais MAÏA-Africa) dans le domaine des produits de soins et d’hygiène, nous renouvelons notre engagement avec la société Intelligent Insect Control dans le domaine de la Pulvérisation Intra-Domiciliaire (PID).

Development and Testing of Long-Lasting IRS Products While Revising the WHO Test Protocol

JOURNAL OF PUBLIC HEALTH INTERNATIONAL – Volume 3 / Issue 4 – Mars 2021

Ole Skovmand 1, Gisèle Ongmayeb 2, Roch Kounbobr Dabiré 3, Moussa Namountougou 3, Benson Georges Meda 3, Trung Trang 4, Duoc Dang 4, Tuan Nguyen 4

1 Intelligent Insect Control SARL, Montpellier, France; 2 Capsulae, Nantes, France; 3 Centre Muraz, Bobo Dioulasso, Burkina Faso; 4 Biolytrics Laboratory, Hanoi, Vietnam.

Abstract
The paper describes the development of a long-lasting product for Intra-domicile residual spray (IRS) and shows it is possible to obtain a residual effect of nearly 2 years. However, to obtain that the methods currentlyrecommended by WHO for laboratory evaluation had to be modified and approached methods closer to the semifield and field evaluations as applied in later phases of WHO procedures. Surfaces with high pH resulted in short residual effect unless the formulations were mixed with a silicone coating. Screening in huts constructed for the purpose was realised by dividing the wall surfaces in 25 test plots of 0.5 m² where formulations were applied randomly with more repeats the closer to the final formulation. Mud and concrete surface were more challenging than wood surface and stones and these could be dropped for screening. Wall surfaces heated by sun were repellent to non-blood fed mosquitoes, and the test in huts were limited to the mornings. However, blood fed mosquitoes were not repelled. Cone tests on mud-walls are complicated by the uneven structure of the surface and a better way of attaching cones to avoid mortality errors was developed. Formulations that can be applied and last for two mosquito seasons produce big cost savings for IRS programs, since program costs are mostly application costs.

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